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74, 75, 76, 77 The underlying mechanism of increased eNOS expression likely involves increased endothelial production of hydrogen peroxide, which has been shown to increase the expression of eNOS at the transcriptional and translational level

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Conversely, after treatment with the well-established PKC activator, PMA, Ect2 activation status was significantly up-regulated in HL-1 cells compared with DMSO-treated controls, suggesting that Ect2 activation can be modulated by PKC kinase activity

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Wang et al., 2013a

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50 mM MgCl

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